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Cooper, A.J. & Cernovovsky, Z.

The effects of cyproterone acetate on sleeping and waking penile erections in pedophiles: Possible implications for treatment.

Canadian Journal of Psychiatry, Vol 37(1), 33-39 (1992)

Studied the short term effects in 5 pedophiles of the antiandrogenic drug cyproterone acetate (CPA) on nocturnal penile tumescence (NPT); penile responses to erotic stimuli in the laboratory; and sex hormones (testosterone, leutenizing hormone, follicle stimulating hormone, and prolactin). During the administration of CPA, NPT, lab arousal and hormones measures (except prolactin) all decreased. Waking lab measures were influenced less and were more variable (1 S showed greater arousal) than NPT measures. Results are discussed with reference to the known psychoneuroendocrinology of sleeping and waking erections. (French abstract)

(PA 79:40217)